In vitro and in vivo effects of Nigella sativa in normal and cancerous cell
Keywords:
Nigella sativa, alcoholic extracts, metaphase chromosomes, MCF-7 and HdFn cell lineAbstract
A growing body of evidence has shown over the past ten years that using medicinal plants may enhance the supportive management of a number of ailments. Among these plants, Nigella sativa (N. sativa, family Ranunculaceae) has garnered a lot of attention. Numerous studies on N. sativa's extracts, seeds, and active ingredient thymoquinone have produced evidence that the plant may have some therapeutic promise for treating a variety of ailments, including cancer.
Through Pubmed, the terms "N. sativa and cancer," "N. sativa," "N. sativa and metastasis," and "N. sativa and cytotoxicity of natural killer cells" were used to apply the selection criteria for references.
With a focus on breast cancer, its anti-metastatic properties, and how N. sativa modifies the cytotoxicity of Natural Killer cells that are essential for tumor surveillance, the goal of this study was to summarize data discussing the effects of N. sativa in cancer generally.
In conclusion, the evidence points to the potential use of N. sativa as a cancer immune system stimulant, as well as for its anti-cancer and antimetastatic effects.
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