Evaluation of antibacterial activity of aloe vera extract on some bacterial pathogens

Authors

  • Onuoha Udumma Nsofor Department of Microbiology, College of Natural Sciences, Michael Okpara University of Agriculture, Umudike, P.M.B. 7267
  • Alaebo Prince Ogochukwu Department of Biochemistry, College of Natural Sciences, Michael Okpara University of Agriculture, Umudike, P.M.B. 7267 Umuahia, Abia State, Nigeria
  • Appeh Osita Gabriel Department of Microbiology, College of Natural Sciences, Michael Okpara University of Agriculture, Umudike, P.M.B. 7267 Umuahia, Abia State, Nigeria
  • Enya Emmanuel Department of Microbiology, College of Natural Sciences, Michael Okpara University of Agriculture, Umudike, P.M.B. 7267 Umuahia, Abia State, Nigeria
  • Chukwuma Maduako Linus Department of Biochemistry, College of Natural Sciences, Michael Okpara University of Agriculture, Umudike, P.M.B. 7267 Umuahia, Abia State, Nigeria

Keywords:

aloe vera, concentration, inhibition, bactericidal

Abstract

The antibacterial activity of Aloe Vera extract was tested on pathogenic bacteria (Escherichia coli, Pseudomonas aeruginosa and Bacillus cereus) at different concentration of 40, 80, 120mg/ml using agar well diffusion method. Two aqueous extracts and ethanol were used. The ethanol extracts shows a high inhibition activity which revealed maximum inhibition on E. coli at the average of (11.3 ± 1.52 to 21.6 ± 2.08) Pseudomonas aeruginosa (15.6 1.15 to 23.6 0.58) and Bacillus cereus (15.6 ± 1.52 to 19.3 ± 1.52) compared with the average of the pathogenic organism on aqueous extract which show the minimum inhibition on E. coli (8.6 1.24 to 13.3 l.53), Bacillus cereus (12.6 ± 0.41 to 16.3 0.59), and Pseudomonas aeruginosa (11.51 1.00 to 17.7 1.52). Ethanol extract of aloe vera has a better inhibition than the aqueous extract. The minimum inhibitory concentration (MIC) of the aqueous extracts on the test organism was between 12.5 to 25mg /ml and ethanol extract between 6.25 to 12.5mg/ml. The minimum bactericidal concentration (MBC) of the aqueous extract on the test organisms ranged between 25 to 50mg/ml and on ethanol extract between 12.5 to 25mg/ml. These results suggest that aloe Vera gel extract with ethanol can be used as antibactericidal agent on human pathogens for medication, cosmetic and food purposes.

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Published

2023-03-09

How to Cite

[1]
O. U. Nsofor, A. P. Ogochukwu, A. O. Gabriel, E. Emmanuel, and C. Maduako Linus, “Evaluation of antibacterial activity of aloe vera extract on some bacterial pathogens”, Int. J. Phytol. Res., vol. 3, no. 1, pp. 26–29, Mar. 2023.

Issue

Vol. 3 No. 1 (2023)

Section

Articles

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