Case series report: neonatal meningitis and sepsis by Elizabethkingia meningoseptica with complications of hydrocephalus and systemic inflammatory responses

Authors

  • Dr. Sahithi Dwarampudi Fellow in Neonatology, M S Ramaiah Medical College and Hospital, Bangalore, India
  • Dr. Pradeep GCM HOD, Department of Neonatology, M S Ramaiah Medical College and Hospital, Bangalore, India
  • Dr. Krithika M V Associate Professor, Department of Neonatology, M S Ramaiah Medical College and Hospital, Bangalore, India
  • Dr. Sharan Bavasya Associate Professor, Department of Neonatology, M S Ramaiah Medical College and Hospital, Bangalore, India

Keywords:

Elizabethkingia meningoseptica, neonatal sepsis, meningitis, hydrocephalus, multi-system inflammatory syndrome, neonatal intensive care

Abstract

Elizabethkingia meningoseptica is an opportunistic pathogen increasingly implicated in severe, multidrug-resistant neonatal infections within hospital settings. This case series highlights three neonates diagnosed with E. meningoseptica -associated meningitis and septicemia, each complicated by unique clinical progressions involving refractory seizures, hydrocephalus, multi-system inflammatory responses, and congenital anomalies. Management required a tailored, multi-disciplinary approach, emphasizing the pathogen's role in high-risk neonatal cases and the importance of early, precise diagnostics and intensive care.

References

Kim KK, Kim MJ, Park MY. Elizabethkingia meningoseptica infections: Clinical manifestations and antibiotic susceptibility in a pediatric population. Pediatric Infectious Disease Journal. 2015;34(9):935-937.

Rahman S, Maheshwari M, Dutta S, Saha B. Outbreak of multidrug-resistant Elizabethkingia meningoseptica in a neonatal intensive care unit: Clinical and environmental perspectives. Journal of Tropical Pediatrics. 2020;66(2):148-156.

Da Silva PS, De Carvalho WB, De Sousa FF. Neonatal Elizabethkingia meningoseptica infections: A review of an emergent pathogen. Current Pediatric Research. 2013;17(2):67-71.

Chiu CH, Waddingdon M, Greenberg D, Palazzi DL. Elizabethkingia meningoseptica meningitis in neonates: A review. Pediatrics International. 2016;58(2):111-118.

Mishra A, Das D, Sahoo R, Jena J. Elizabethkingia meningoseptica infections in neonates: Clinical outcomes, resistance patterns, and implications for therapy. Indian Journal of Medical Microbiology. 2021;39(3):389-392.

Fernández-Ruiz M, Álvarez M, San Juan R. Multidrug-resistant Elizabethkingia meningoseptica: Molecular insights and implications for neonatal health care. Frontiers in Pediatrics. 2020;8:435.

Giri P, Prasad K, Barik R. Elizabethkingia meningoseptica in NICUs: Risk factors, prevention, and management strategies. Infectious Diseases in Clinical Practice. 2018;26(5):255-260.

Downloads

Published

2024-10-07

How to Cite

[1]
S. Dwarampudi, P. GCM, K. M V, and S. Bavasya, “Case series report: neonatal meningitis and sepsis by Elizabethkingia meningoseptica with complications of hydrocephalus and systemic inflammatory responses”, J. A. Med. Sci, vol. 4, no. 4, pp. 01–02, Oct. 2024.

Issue

Section

Articles