Journal of Advance Medical Sciences https://dzarc.com/medical <p><strong>Journal of Advance Medical Sciences</strong> is a peer-reviewed, refereed, and open access journal that focuses on critical and creative research and provides an open access research journal platform for scholars and researchers to exchange their research work results among professionals throughout the world. This journal publishes research articles in all fields of Medical science but is not limited to.</p> en-US dzarc.medical@gmail.com (Dzarc Publications) ssaxena1@amity.edu (Dr. Sarika Saxena) Mon, 01 Apr 2024 00:00:00 +0000 OJS 3.3.0.10 http://blogs.law.harvard.edu/tech/rss 60 Effectiveness of an educational program on patient's dietary knowledge after recovery from myocardial infarction https://dzarc.com/medical/article/view/496 <p><strong>Background:</strong> Acute myocardial infarction is one of the most common health problems in the world and the leading cause of death, it represents a clinical condition characterized by rapidly developing critical myocardial ischemia. This indicates the requirement that MI patients need to adherence of a healthy diet and receive required education on changing dietary pattern, dietary regimens, including the composition, calorie intake, and feeding patterns, represent major factors affecting of myocardial infarction patients.</p> <p><strong>Aim of this study:</strong> The study aims to evaluate the patient's dietary knowledge after recovery from myocardial infarction, and to find out the association between the effectiveness of educational program and patient's socio-demographic characteristics (age, gender, level of education, occupational status and residential area).</p> <p><strong>Methodology:</strong> The quasi-experimental design has been carried out to evaluate the patient's dietary knowledge after recovery from myocardial infarction, in the cardiac outpatient clinic at Al-Diwaniyah teaching hospital for the period from 17<sup>th</sup> January 2023 to 3<sup>th</sup> May, 2024. Non probability (purposive) sample of (60) patients were selected who are recovery from myocardial infraction for at least four weeks and they had attended of cardiac outpatient clinics of AL Diwaniyah teaching hospital, the sample was divided into two groups each one consisted of (30) patients as study and control group. The study instrument comprised of (3) parts: Part I- demographical characteristics of the patient which consist of (7) items. Part II- Clinical characteristics data which consists of (3) items and Part III- Patient's Dietary Knowledge which consists of (20) close-ended statements.</p> <p><strong>Results:</strong> Results of the study shows the patient's dietary knowledge at post-test were improved to good dietary patients' knowledge in mean (2.35) regarding study group. While the dietary patients' knowledge at the Pre-Test and Post-Test Measurements for the control group were poor in pre-test (1.62), and post-test (1.61).</p> <p><strong>Conclusions: </strong>The researcher concludes that the educational program was effective in improving the patient's dietary knowledge about DASH diet, and there were statistical significant differences between the study and control group at post-test measurements regarding dietary patients' knowledge at <em>p</em> value &lt;0.05.</p> Sabri Shather Hadi, Khalida Mohammed Khudur Copyright (c) 2024 Sabri Shather Hadi, Khalida Mohammed Khudur https://creativecommons.org/licenses/by/4.0 https://dzarc.com/medical/article/view/496 Mon, 06 May 2024 00:00:00 +0000 Evaluation of the effect of patient related factors on bacterial periodontitis in Salah al-Din city in Iraq https://dzarc.com/medical/article/view/529 <p>One of the most common bacterial infections in people is periodontal disease. its primary reasons for tooth loss. The primary cause of these oral ulcers is the colonization of harmful microorganisms on the surfaces of the mouth. These microorganisms differ based on the lesion under investigation, the length of their development, and the host.</p> <p><strong>Aim of the study</strong></p> <p>The study aimed to evaluate the bacterial causes of periodontitis and determined their antibiotic resistance and explain the relation between the bacterial spp. isolate with different patient’s variables.</p> <p><strong>Methods </strong></p> <p>90 specimens were collected from patients with gingivitis resulting from orthodontic and placement from medical clinics and health centers in Balad district in Salah al-Din Governorate after they were diagnosed in bed with gingivitis by specialist doctors. Swabs of the inflamed gums were taken and then cultured on appropriate culture media and appropriate diagnostic tests were performed, the disc diffusion method were used for antibiotics susceptibility test for all isolated bacteria.</p> <p><strong>Results</strong></p> <p>The study showed that periodontitis was most prevalent in teenagers (65%) and in female (63.3%) with mixed diet (61.6%) and urban residence (74.7%). <em>Streptococcus pyogenes</em> was most common isolated bacteria from patients (61.9%) also other bacteria were obtained. <em>Strep. pyogenes</em> was sensitive to Ampicillin, Augmentin and Ceftazidime while resist to metronidazole and tetracycline.</p> <p><strong>Conclusion</strong></p> <p>The periodontal status is influenced by numerous patient-related local variables. The most resistant bacteria in the current investigation, <em>Streptococcus pyogenes</em>, demonstrated considerable antibiotic sensitivity.</p> Amna Burer Shukr, Ayad M. Gaidan Copyright (c) 2024 https://creativecommons.org/licenses/by/4.0 https://dzarc.com/medical/article/view/529 Tue, 07 May 2024 00:00:00 +0000 Oral anticancer prediction of hexadecenoic acid on p50 target receptor by molecular docking https://dzarc.com/medical/article/view/537 <p>Ambonese banana stem extract (Musa paradisiaca var. sapientum) has been proven to contain the active compound hexadecenoic acid (Hexa) which can suppress the growth of cancer cells through the apoptosis process. The aims to determine HA interaction to nuclear factor-kappa-B p50/ReLA for the development of oral anticancer drugs through molecular docking. In silico study carried out include prediction of activity spectra of substances (PASS), drug-likeness analysis based on the lipinski rule of five principles, absorption, distribution, metabolism, excretion, and toxicity (ADMET) study, molecular docking and HA bond visualization (CID: 985), along with the positive control comparison compound 5-fluorouracil (Fluo) (CID: 3385) and the derivative compound 9-octadecenoic acid (Octa) (CID: 445639) which bind to the proteins target RelA (PDB ID: 6NV2). Results data shows HA compounds have potential as anticancer therapy because of their distribution throughout the body and their activity against cancer. Molecular docking shows that HA is predicted to bind more effectively to the binding pocket of both RelA, while 9-octadecenoic acid has a fairly good interaction with RelA when compared to 5-Fluorouracil. From this study, we can conclude that Hexadecenoic acid compound found in Musa paradisiaca var. sapientum (L.) Kuntze represents a breakthrough in developing new drugs with potential and effectiveness against RelA/p50.</p> Naila Mufidah, Hendrik Setia Budi, Retno Indrawati Copyright (c) 2024 https://creativecommons.org/licenses/by/4.0 https://dzarc.com/medical/article/view/537 Wed, 08 May 2024 00:00:00 +0000 Extraction of the posterior maxillary tooth with the crown fracture and dilaceration of palatal roots https://dzarc.com/medical/article/view/538 <p>Caries that are not treated early will cause the tooth structure to be damaged and ultimately untenable, so extraction must be carried out. The process of tooth extraction can experience complications or complicating conditions if there is root dilation. An extraction camay be followed by separated of the root when has a dilaceration root. This paper reported a 57-year-old female patient came to the clinic complaining pain in her teeth in the right upper jaw since a year ago. To enforce diagnostics are used through deep anamnesis to patients and objective examinations. Treatment of a patient is the extraction of the tooth by the method of separation root and medical drugs. The extraction procedure is done and the patient works well without any complication. The extraction perform was done and there is no complication occurs. The procedure for extracting the tooth with a root laceration can be performed by separating the tooth and reducing the surrounding bone to make it easier to remove the tooth from its socket.</p> Ridhofar Akbar Khusnul Abdillah, Koko Muzari, Salsabila Nurmalia, Bambang Tri Hartomo Copyright (c) 2024 https://creativecommons.org/licenses/by/4.0 https://dzarc.com/medical/article/view/538 Wed, 15 May 2024 00:00:00 +0000