Effect of L-thyroxin on left ventricular diastolic dysfunction among subclinical hypothyroid patients

Authors

  • Dr. Shahid Amin Malla MD Medicine, GMC Srinagar, Kashmir, Jammu & Kashmir, India
  • Dr. Irfan Ali Associate Professor, Postgraduate Department of Medicine, GMC, Srinagar, Kashmir, Jammu & Kashmir, India
  • Dr. Tariq Ahmad Malla Registrar, General Surgery, GMC, Srinagar, Kashmir, Jammu & Kashmir, India
  • Dr. Sakeena MDS, Registrar SKIMS, Soura, Srinagar, Kashmir, Jammu & Kashmir, India

Keywords:

thyroxin, ventricular diastolic dysfunction, subclinical hypothyroid patients

Abstract

The present study draws special attention to find the effect of thyroxin in subclinical hypothyroid patients with left ventricular diastolic dysfunction. The aim of the study is to assess the left ventricular diastolic function in patients with subclinical hypothyroidism after starting treatment with thyroxin. In this study all patients were above the age 18 years having subclinical hypothyroidism with left ventricular diastolic dysfunction. Apart from the detailed clinical history, relevant clinical examination was done in very participants. This study shows that after starting thyroxin in subclinical hypothyroid patients with left ventricular diastolic dysfunction, there was drastic improvement in left ventricular diastolic function.

References

Canaris GJ, Manowitz NR, Mayor G, Ridgway EC. The Colorado Thyroid Disease Prevalence Study. Arch Intern Med, 2000; 160:526-34.

Vanderpump MP, Tunbridge WM, French JM, et al. The incidence of thyroid disorders in the community: a twentyyear follow-up of the Whickham Survey. Clin Endocrinol (Oxf), 1995; 43:55-68.

Surks MI, Ortiz E, Daniels GH, et al. Subclinical thyroid disease: scientific review and guidelines for diagnosis and management. JAMA, 2004; 291:228- 38.

Rodondi N, Den Elzen WP, Bauer DC, et al. Subclinical hypothyroidism and the risk of coronary heart disease and mortality. JAMA, 2010; 304:1365-74.

Meyerovitch J, Rotman-Pikielny P, et al. Serum thyrotropin measurements in the community: five-year follow-up in a large network of primary care physicians. Arch Intern Med, 2007; 167:1533-8.

Kumar Pankaj et al. Study of LV functions in patients of subclinical hypothyroidism in patients coming to rural medical college of Sub-Himalayan region of India, 2015.

Meena CL et al. Assessment of Left Ventricular Diastolic Dysfunction in Sub-clinical Hypothyroidism, 2012.

Bernadette Biondi et al. Studies on the Clinical Significance of Subclinical Thyroid Dysfunction. Endocrine Reviews, 2008; 29:76-131.

Biondi, Serfino Fazio, et al. Left Ventricular Diastolic Dysfunction in Patients with Subclinical Hypothyroidism. The journal of Clinical Endocrinology & Metabolism, 1999; 84(6):2064-2067.

Marco Zuin et al. Left ventricular diastolic dysfunction with subclinical hypothyroidism, 2016.

Yuthika Malhotra et al. Echocardiographic evaluation of left ventricular diastolic dysfunction in subclinical hypothyroidism. Endocr Res, 2017.

TK Mishra et al. Left ventricular dysfunction in patients with subclinical hypothyroidism and its reversibility after hormone therapy. J Assoc Physicians India, 2005.

HCCE Villae et al. Thyroid hormone replacement for subclinical hypothyroidism. Cochrane Database Syst Rev, 2007.

Mehmet Yazici et al. Effects of thyroxin therapy on cardiac function in patients with subclinical hypothyroidism. Int J Cardiol, 2004.

F Franzon et al. Effect of l- thyroxin treatment on left ventricular function in subclinical hypothyroidism. Biomed Pharmacother, 2006.

Downloads

Published

2021-10-23

How to Cite

[1]
S. A. Malla, I. Ali, T. A. Malla, and Sakeena, “Effect of L-thyroxin on left ventricular diastolic dysfunction among subclinical hypothyroid patients”, J. A. Med. Sci, vol. 1, no. 2, pp. 01–03, Oct. 2021.

Issue

Section

Articles