Anti-inflammatory and antibacterial properties of almond by-products as wound healing potential agent: a review
Keywords:
Almonds, Wound healing, Anti-inflammatory, AntibacterialAbstract
Patients who have suffered significant trauma are at higher risk of developing bacterial infections which could lead to bacteremia and prolonged inflammation on wound healing process. Thus, antibacterial and anti-inflammatory agents are essential to facilitate wound healing. Since natural substances have a tendency to be less toxic, therapeutic agents like almonds are frequently used. This study is aimed to summarize the antibacterial and anti-inflammatory properties of almond by-products. According to phytochemical investigations, almond by-products phenolic compounds such as flavonoids, tannin, phenolic acids, and aldehyde. Several studies have found that almond by-products are able to inhibit the growth of some bacterial strains of gram negative and positive. In addition, it has been demonstrated that almond by-products have anti-inflammatory properties through reducing the expression of pro-inflammatory cytokines. Thus, almond by-products are potential as wound healing agents to prevent further infections through its anti-inflammatory and antibacterial activities. Therefore, additional research such as clinical trials, are recommended to investigate its effectiveness on wound healing and safety application.
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