The relationship of serum level of interleukin-4 with the level of anti–hepatitis b antibodies


  • Marwa Jassim Mohammed Department of Biology, College of Science, University of Tikrit, Salah Al-Din, Iraq
  • Dr. Halah Abdulkhaliq Awadh Department of Biology, College of Science, University of Tikrit, Salah Al-Din, Iraq
  • Dr. Ayad M. Gaidan Department of Biology, College of Science, University of Tikrit, Salah Al-Din, Iraq


liver infection, antibodies, HBV patient, Iraq


Hepatitis is a liver infection and inflammation that can be acute or chronic with a diverse etiology, including viruses, bacteria, medicines, and hazardous chemicals. Hepatitis B is the most common causes of chronic and acute hepatitis disorders worldwide. A cross-sectional study was carried out in Salahaldeen governorate from 15th of December 2021 to 25th of August 2022.The study included 90 hepatitis patients with hepatitis B, ranging in age from18 to 61 years. These individuals were hospitalized to general Sammarra hospital. The control group, which was matched to the patients analyzed, consisted of 40 people who appeared to be healthy. 5ml of blood was taken from each patient in this study for the purpose of ELISA testing to check HBs Ag, antibodies to both HBs, IL4.The result showed that all patient with hebatitis B had HBsAg and the number of people with HBV in males more than female. The mean serum level of IL-4 in HBV patients was (50.31±16.34) which was lower than that of control (82.97±21.63 pg/ml) with a significant difference. The mean serum level of anti-HBs IgG in HBV patients was (9.48 ±4.1 U/L) which was lower than that of control (14.77±7.22 U/L) with a significant difference.


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How to Cite

Mohammed, M. J., Awadh, H. A., & Gaidan, A. M. (2023). The relationship of serum level of interleukin-4 with the level of anti–hepatitis b antibodies. Journal of Advanced Education and Sciences, 3(3), 01–04. Retrieved from